# OnCo record rindopepimut (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/rindopepimut/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "rindopepimut" ;
  schema:name "Rindopepimut"@en ;
  schema:description "Rindopepimut is a peptide vaccine against EGFRvIII, a mutant protein found only on some glioblastomas. After a phase 2 that beat historical controls, the 745-patient double-blind phase 3 ACT IV found no benefit in 2016, and tumours in both arms had lost EGFRvIII at recurrence, a lesson in antigen escape."@en ;
  schema:url <https://onco.cc/drugs/rindopepimut/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01480479> ;
  onco:status "negative" ;
  onco:modality "Peptide vaccine (EGFRvIII)" ;
  onco:cancers <https://onco.cc/cancers/glioblastoma/> ;
  onco:technologies <https://onco.cc/technologies/shared-antigen-vaccine/> ;
  onco:targets <https://onco.cc/targets/egfr/> ;
  onco:companies <https://onco.cc/companies/celldex/> ;
  onco:terms <https://onco.cc/terms/egfrviii/> ;
  onco:trials <https://onco.cc/trials/act-iv/> .