# OnCo record ripk2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ripk2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ripk2" ;
  schema:name "RIPK2"@en ;
  schema:alternateName "receptor interacting serine/threonine kinase 2"@en, "RIP2"@en, "RICK"@en, "RIPK2" ;
  schema:description "RIPK2 relays alarm signals from the NOD1 and NOD2 sensors that detect bacteria, switching on inflammation. It has been proposed as a cancer target both for its effects on immune cells and, in prostate cancer, for helping tumours spread; a RIPK2 inhibitor is in an early melanoma trial."@en ;
  schema:url <https://onco.cc/targets/ripk2/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10020>, <https://www.uniprot.org/uniprotkb/O43353/entry>, <https://www.ncbi.nlm.nih.gov/gene/8767>, <https://doi.org/10.1038/s41467-022-28340-6> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10020>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000104312>, <https://www.uniprot.org/uniprotkb/O43353/entry>, <https://www.ncbi.nlm.nih.gov/gene/8767> ;
  onco:cancers <https://onco.cc/cancers/prostate-mcrpc/>, <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/opm-101/> .