# OnCo record risk-directed-first-line-rcc (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/risk-directed-first-line-rcc/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "risk-directed-first-line-rcc" ;
  schema:name "IMDC risk → first-line regimen choice (RCC)"@en ;
  schema:description "A simple clinical score decides between two immunotherapies together or one immunotherapy with a targeted pill."@en ;
  schema:url <https://onco.cc/pairings/risk-directed-first-line-rcc/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02231749> ;
  onco:cancers <https://onco.cc/cancers/rcc/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/ipilimumab/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/axitinib/>, <https://onco.cc/drugs/cabozantinib/>, <https://onco.cc/drugs/lenvatinib/> ;
  onco:terms <https://onco.cc/terms/imdc-risk/>, <https://onco.cc/terms/sarcomatoid-rcc/> ;
  onco:pairs <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/kinase-inhibitors/> .