# OnCo record rnf43 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/rnf43/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "rnf43" ;
  schema:name "RNF43"@en ;
  schema:alternateName "ring finger protein 43"@en, "E3 ubiquitin-protein ligase RNF43"@en, "FLJ20315"@en, "RNF124"@en, "DKFZp781H0392"@en, "RNF43" ;
  schema:description "RNF43 (E3 ubiquitin-protein ligase RNF43) is an enzyme. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Pancreatic ductal adenocarcinoma, Colorectal cancer, Gastric & gastro-oesophageal junction cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/rnf43/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:18505>, <https://www.uniprot.org/uniprotkb/Q68DV7/entry>, <https://www.ncbi.nlm.nih.gov/gene/54894>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000108375> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:18505>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000108375>, <https://www.uniprot.org/uniprotkb/Q68DV7/entry>, <https://www.ncbi.nlm.nih.gov/gene/54894> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/lung-cancer/> ;
  onco:pathways <https://onco.cc/pathways/wnt/> .