# OnCo record ros1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ros1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ros1" ;
  schema:name "ROS1"@en ;
  schema:description "A gene fusion in about 1-2% of lung cancers that responds for years to targeted pills, now in their third generation."@en ;
  schema:url <https://onco.cc/targets/ros1/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/ROS1>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10261>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000047936>, <https://www.uniprot.org/uniprotkb/P08922/entry>, <https://www.ncbi.nlm.nih.gov/gene/6098> ;
  owl:sameAs <http://www.wikidata.org/entity/Q18031208> ;
  schema:citation <https://en.wikipedia.org/wiki/ROS1> ;
  onco:tag "driver", "kinase" ;
  schema:alternateName "ROS1" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1986"^^xsd:gYear ;
  onco:related <https://onco.cc/biomarkers/ros1-fusion/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/repotrectinib/>, <https://onco.cc/drugs/zidesamtinib/>, <https://onco.cc/drugs/taletrectinib/>, <https://onco.cc/drugs/oncomine-dx-target-test/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/>, <https://onco.cc/pathways/pi3k-akt-mtor/> ;
  onco:terms <https://onco.cc/terms/gene-fusion/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-bergethon-ros1-rearrangements-lung-jco-2012/> .