# OnCo record runx1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/runx1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "runx1" ;
  schema:name "RUNX1"@en ;
  schema:alternateName "RUNX family transcription factor 1"@en, "Runt-related transcription factor 1"@en, "PEBP2A2"@en, "AMLCR1"@en, "AML1"@en, "CBFA2"@en, "RUNX1" ;
  schema:description "RUNX1 (Runt-related transcription factor 1) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor, a biomarker and a fusion partner, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Leukaemia, Myeloproliferative neoplasms, Non-Hodgkin lymphoma and 5 more."@en ;
  schema:url <https://onco.cc/targets/runx1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10471>, <https://www.uniprot.org/uniprotkb/Q01196/entry>, <https://www.ncbi.nlm.nih.gov/gene/861>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000159216> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10471>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000159216>, <https://www.uniprot.org/uniprotkb/Q01196/entry>, <https://www.ncbi.nlm.nih.gov/gene/861> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/mds/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/salivary-gland/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/lung-cancer/> ;
  onco:pathways <https://onco.cc/pathways/aml-signalling/> .