# OnCo record sample-size-re-estimation (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/sample-size-re-estimation/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "sample-size-re-estimation" ;
  schema:name "Statistical power, sample size and re-estimation"@en ;
  schema:alternateName "sample size re-estimation"@en, "sample size reassessment"@en, "blinded sample size re-estimation"@en, "unblinded sample size re-estimation"@en, "sample size calculation"@en, "power calculation"@en, "powered to detect"@en, "80% power"@en, "90% power"@en, "the trial was powered"@en, "adequately powered"@en, "event-driven"@en, "events required"@en, "target number of events"@en, "number of events"@en, "information fraction"@en, "effect size"@en, "assumed hazard ratio"@en, "assumed effect"@en, "conditional power"@en, "promising zone"@en, "expected number of events"@en ;
  schema:description "Before a trial starts, statisticians work out how many patients, or how many deaths or relapses, are needed to detect the benefit they hope for; an adaptive trial can check that guess part way through and enlarge itself if the guess was wrong."@en ;
  schema:url <https://onco.cc/terms/sample-size-re-estimation/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Statistical_power> ;
  schema:citation <https://en.wikipedia.org/wiki/Statistical_power>, <https://www.fda.gov/regulatory-information/search-fda-guidance-documents/adaptive-design-clinical-trials-drugs-and-biologics-guidance-industry>, <https://www.ich.org/page/efficacy-guidelines> ;
  onco:related <https://onco.cc/terms/statistical-significance/>, <https://onco.cc/terms/seamless-adaptive/>, <https://onco.cc/terms/interim-analysis/>, <https://onco.cc/terms/group-sequential-design/>, <https://onco.cc/terms/trial-failure-modes/>, <https://onco.cc/terms/confidence-interval/>, <https://onco.cc/terms/data-maturity/>, <https://onco.cc/terms/hazard-ratio/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:trials <https://onco.cc/trials/dream3r/>, <https://onco.cc/trials/add-aspirin/>, <https://onco.cc/trials/adaura/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/> .