# OnCo record scrambler-therapy (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/scrambler-therapy/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "scrambler-therapy" ;
  schema:name "Scrambler therapy (Calmare) for chemotherapy nerve pain"@en ;
  schema:description "A surface electrical device that is said to replace pain signals with signals the brain reads as normal. People treated with it often feel better, but in the only trial that compared it with a dummy device there was no difference between the two, so what is being felt may be the attention and the expectation rather than the machine."@en ;
  schema:url <https://onco.cc/technologies/scrambler-therapy/> ;
  schema:dateModified "2026-10-02"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Transcutaneous_electrical_nerve_stimulation> ;
  schema:citation <https://doi.org/10.1177/0825859719827589>, <https://doi.org/10.1007/s00520-019-04881-3>, <https://doi.org/10.1186/s43046-026-00347-w>, <https://doi.org/10.1200/JCO.20.01399> ;
  onco:status "emerging" ;
  onco:tag "rejuvenation", "survivorship", "evidence:insufficient" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:sections <https://onco.cc/fronts/rejuvenation/>, <https://onco.cc/fronts/supportive-care/>, <https://onco.cc/fronts/devices/> ;
  onco:technologies <https://onco.cc/technologies/cipn-recovery-and-treatment/>, <https://onco.cc/technologies/acupuncture-chemotherapy-neuropathy/>, <https://onco.cc/technologies/pain-management/> ;
  onco:drugs <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/bortezomib/> ;
  onco:terms <https://onco.cc/terms/peripheral-neuropathy/>, <https://onco.cc/terms/placebo/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-toxicity-qol/> .