# OnCo record sdhb (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/sdhb/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "sdhb" ;
  schema:name "SDHB"@en ;
  schema:alternateName "succinate dehydrogenase complex iron sulfur subunit B"@en, "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial"@en, "SDH1"@en, "SDHB" ;
  schema:description "SDHB (Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial) is an enzyme. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Neuroendocrine tumours, Breast cancer and Gastrointestinal stromal tumour."@en ;
  schema:url <https://onco.cc/targets/sdhb/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10681>, <https://www.uniprot.org/uniprotkb/P21912/entry>, <https://www.ncbi.nlm.nih.gov/gene/6390>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000117118> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10681>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000117118>, <https://www.uniprot.org/uniprotkb/P21912/entry>, <https://www.ncbi.nlm.nih.gov/gene/6390> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/neuroendocrine/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/gist/> .