# OnCo record self-amplifying-rna (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/self-amplifying-rna/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "self-amplifying-rna" ;
  schema:name "Self-amplifying and circular RNA therapeutics"@en ;
  schema:description "RNA drugs that copy themselves inside the cell, or are made as a loop so they last longer. Both aim to get more protein from a smaller dose."@en ;
  schema:url <https://onco.cc/technologies/self-amplifying-rna/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?term=self-amplifying%20RNA%20cancer> ;
  onco:status "phase-1" ;
  onco:tag "frontier", "promising" ;
  onco:sections <https://onco.cc/fronts/immunotherapy/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/shared-antigen-vaccine/>, <https://onco.cc/technologies/in-vivo-car-t/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/moderna/>, <https://onco.cc/companies/orna-therapeutics/> .