# OnCo record serrated-pathway (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/serrated-pathway/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "serrated-pathway" ;
  schema:name "Serrated pathway"@en ;
  schema:alternateName "serrated neoplasia pathway"@en, "sessile serrated lesion pathway"@en, "serrated polyp pathway"@en, "CpG island methylator phenotype pathway"@en ;
  schema:description "The serrated pathway is the second route to bowel cancer, running not through the familiar mushroom-shaped polyp but through flat, pale, saw-toothed lesions that are easy to miss at colonoscopy and rarely bleed. It accounts for about three in ten bowel cancers and for most of the ones whose DNA proofreading has broken down by accident rather than by inheritance."@en ;
  schema:url <https://onco.cc/terms/serrated-pathway/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Sessile_serrated_lesion> ;
  schema:citation <https://doi.org/10.1111/his.12055>, <https://doi.org/10.1080/17474124.2025.2509797>, <https://doi.org/10.1136/gutjnl-2019-319858>, <https://doi.org/10.1111/his.13975> ;
  onco:tag "gi", "colorectal" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/colorectal-serrated-adenocarcinoma/>, <https://onco.cc/cancers/msi-high-colorectal/>, <https://onco.cc/cancers/braf-v600e-colorectal/>, <https://onco.cc/cancers/colon-cancer/> ;
  onco:technologies <https://onco.cc/technologies/colorectal-screening/>, <https://onco.cc/terms/colonoscopy/>, <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:targets <https://onco.cc/targets/braf/>, <https://onco.cc/targets/kras/> ;
  onco:terms <https://onco.cc/terms/adenoma-carcinoma-sequence/>, <https://onco.cc/terms/colorectal-polyp-types/>, <https://onco.cc/terms/colonoscopy-surveillance-intervals/>, <https://onco.cc/terms/msi/>, <https://onco.cc/terms/mlh1-promoter-methylation/> .