# OnCo record setd1b (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/setd1b/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "setd1b" ;
  schema:name "SETD1B"@en ;
  schema:alternateName "SET domain containing 1B, histone lysine methyltransferase"@en, "Histone-lysine N-methyltransferase SETD1B"@en, "KIAA1076"@en, "Set1B"@en, "KMT2G"@en, "SETD1B" ;
  schema:description "SETD1B (Histone-lysine N-methyltransferase SETD1B) is a protein that switches other genes on and off. The public catalogues list it as an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Oesophageal cancer, Head and neck squamous cell carcinoma, Ovarian cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/setd1b/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29187>, <https://www.uniprot.org/uniprotkb/Q9UPS6/entry>, <https://www.ncbi.nlm.nih.gov/gene/23067>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000139718> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:29187>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000139718>, <https://www.uniprot.org/uniprotkb/Q9UPS6/entry>, <https://www.ncbi.nlm.nih.gov/gene/23067> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/nsclc/> .