# OnCo record setdb1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/setdb1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "setdb1" ;
  schema:name "SETDB1"@en ;
  schema:alternateName "SET domain bifurcated histone lysine methyltransferase 1"@en, "Histone-lysine N-methyltransferase SETDB1"@en, "KG1T"@en, "KIAA0067"@en, "KMT1E"@en, "TDRD21"@en, "SETDB1" ;
  schema:description "SETDB1 (Histone-lysine N-methyltransferase SETDB1) is a protein that switches other genes on and off. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Breast cancer, Colorectal cancer, Hepatocellular carcinoma and 5 more."@en ;
  schema:url <https://onco.cc/targets/setdb1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10761>, <https://www.uniprot.org/uniprotkb/Q15047/entry>, <https://www.ncbi.nlm.nih.gov/gene/9869>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143379> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10761>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143379>, <https://www.uniprot.org/uniprotkb/Q15047/entry>, <https://www.ncbi.nlm.nih.gov/gene/9869> ;
  onco:related <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/mesothelioma/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/cll/> .