# OnCo record sf3b1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/sf3b1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "sf3b1" ;
  schema:name "SF3B1"@en ;
  schema:alternateName "splicing factor 3b subunit 1"@en, "Splicing factor 3B subunit 1"@en, "SAP155"@en, "SF3b155"@en, "PRPF10"@en, "Prp10"@en, "Hsh155"@en, "SF3B1" ;
  schema:description "SF3B1 (Splicing factor 3B subunit 1) is a gene that drives cell growth when it is altered. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Leukaemia, Non-Hodgkin lymphoma, Myelodysplastic syndromes / neoplasms and 5 more."@en ;
  schema:url <https://onco.cc/targets/sf3b1/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10768>, <https://www.uniprot.org/uniprotkb/O75533/entry>, <https://www.ncbi.nlm.nih.gov/gene/23451>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115524> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "oncogene" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:10768>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115524>, <https://www.uniprot.org/uniprotkb/O75533/entry>, <https://www.ncbi.nlm.nih.gov/gene/23451> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/mds/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/hcc/> ;
  onco:pathways <https://onco.cc/pathways/rna-splicing/> .