# OnCo record sidedness (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/sidedness/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "sidedness" ;
  schema:name "Sidedness (left vs right colon)"@en ;
  schema:description "Where in the colon a tumour starts changes its biology and which drugs work. Left-sided tumours respond to EGFR antibodies; right-sided ones do not."@en ;
  schema:url <https://onco.cc/terms/sidedness/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Colorectal_cancer> ;
  schema:citation <https://clinicaltrials.gov/study/NCT02394795>, <https://doi.org/10.1093/annonc/mdx175>, <https://www.nice.org.uk/guidance/ng151/chapter/Recommendations>, <https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/bowel-cancer/incidence> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/colon-cancer/>, <https://onco.cc/cancers/rectal-cancer/> ;
  onco:targets <https://onco.cc/targets/egfr/>, <https://onco.cc/targets/braf/> ;
  onco:terms <https://onco.cc/terms/conversion-therapy-colorectal/>, <https://onco.cc/terms/liver-limited-metastatic-colorectal/> ;
  onco:trials <https://onco.cc/trials/paradigm/>, <https://onco.cc/trials/crystal-fire3/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-arnold-primary-tumour-side-ras-wild-type-ann-oncol-2017/>, <https://onco.cc/key-papers/paper-tejpar-tumour-location-crystal-fire3-jama-oncol-2017/>, <https://onco.cc/key-papers/paper-missiaglia-distal-proximal-colon-cancers-ann-oncol-2014/>, <https://onco.cc/key-papers/paper-loree-tumour-location-continuum-colorectal-ccr-2018/>, <https://onco.cc/key-papers/paper-yaeger-metastatic-colorectal-genomic-landscape-cancer-cell-2018/> .