# OnCo record sins-trial (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/sins-trial/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "sins-trial", "ISRCTN48755084" ;
  schema:name "SINS (surgical excision against imiquimod cream for basal cell carcinoma)"@en ;
  schema:alternateName "SINS"@en, "Surgery versus Imiquimod for Nodular and Superficial basal cell carcinoma"@en, "ISRCTN48755084"@en ;
  schema:description "The largest trial of a cream against an operation for the commonest cancer found the cream is worse, and stayed worse at five years. About one person in six treated with the cream still needed something else done, against one in fifty after surgery. It is still a reasonable choice for some people, but it is not equivalent."@en ;
  schema:url <https://onco.cc/trials/sins-trial/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://www.isrctn.com/ISRCTN48755084>, <https://clinicaltrials.gov/study/NCT00066872>, <https://doi.org/10.1016/S1470-2045(13)70530-8>, <https://doi.org/10.1016/j.jid.2016.10.019>, <https://pubmed.ncbi.nlm.nih.gov/24332516/> ;
  onco:status "negative" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/basal-cell-carcinoma/>, <https://onco.cc/cancers/skin-cancer/> ;
  onco:drugs <https://onco.cc/drugs/imiquimod/> ;
  onco:institutions <https://onco.cc/institutions/nottingham-cancer-centre/> ;
  onco:terms <https://onco.cc/terms/topical-and-destructive-treatment-bcc/>, <https://onco.cc/terms/surgical-margins-keratinocyte-cancer/> ;
  onco:trials <https://onco.cc/trials/mal-pdt-imiquimod-fluorouracil-superficial-bcc/>, <https://onco.cc/trials/scin-trial/>, <https://onco.cc/trials/mohs-versus-excision-facial-bcc/> ;
  onco:people <https://onco.cc/people/hywel-williams/> .