# OnCo record sirpa (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/sirpa/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "sirpa" ;
  schema:name "SIRPA"@en ;
  schema:alternateName "signal regulatory protein alpha"@en, "Tyrosine-protein phosphatase non-receptor type substrate 1"@en, "SHPS1"@en, "MYD-1"@en, "P84"@en, "SHPS-1"@en, "SIRPalpha"@en, "CD172a"@en, "SIRPalpha2"@en, "SIRP-ALPHA-1"@en, "PTPNS1"@en, "SIRPA" ;
  schema:description "SIRPA (Tyrosine-protein phosphatase non-receptor type substrate 1) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver and a tumour suppressor, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Cervical cancer, Colorectal cancer, Non-Hodgkin lymphoma and 1 more."@en ;
  schema:url <https://onco.cc/targets/sirpa/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9662>, <https://www.uniprot.org/uniprotkb/P78324/entry>, <https://www.ncbi.nlm.nih.gov/gene/140885>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198053> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "oncogene" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:9662>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198053>, <https://www.uniprot.org/uniprotkb/P78324/entry>, <https://www.ncbi.nlm.nih.gov/gene/140885> ;
  onco:related <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/aml/> .