# OnCo record slotman-pci-es-sclc (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/slotman-pci-es-sclc/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "slotman-pci-es-sclc" ;
  schema:name "EORTC 08993 (Slotman): prophylactic cranial irradiation in extensive-stage small-cell lung cancer"@en ;
  schema:description "Slotman's trial showed that irradiating the brain before metastases appear cuts symptomatic brain metastases and lengthens survival in extensive-stage small-cell lung cancer, though a later Japanese trial with MRI screening did not confirm the survival gain."@en ;
  schema:url <https://onco.cc/trials/slotman-pci-es-sclc/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMoa071780> ;
  onco:status "positive" ;
  onco:tag "radiation-wave4" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/extensive-stage-sclc/> ;
  onco:technologies <https://onco.cc/technologies/prophylactic-cranial-irradiation/> ;
  onco:companies <https://onco.cc/companies/curie-nki-eortc/> ;
  onco:terms <https://onco.cc/terms/wbrt/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-slotman-n-engl-j-med/> .