# OnCo record smad2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/smad2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "smad2" ;
  schema:name "SMAD2"@en ;
  schema:alternateName "SMAD family member 2"@en, "MADR2"@en, "JV18-1"@en, "MADH2"@en, "SMAD2" ;
  schema:description "SMAD2 (SMAD family member 2) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and an approved or late-stage drug is recorded against it. Tied to Colorectal cancer, Skin cancer, Gastric & gastro-oesophageal junction cancer and 1 more."@en ;
  schema:url <https://onco.cc/targets/smad2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6768>, <https://www.uniprot.org/uniprotkb/Q15796/entry>, <https://www.ncbi.nlm.nih.gov/gene/4087>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000175387> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6768>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000175387>, <https://www.uniprot.org/uniprotkb/Q15796/entry>, <https://www.ncbi.nlm.nih.gov/gene/4087> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/luspatercept/> ;
  onco:pathways <https://onco.cc/pathways/tgf-beta/> .