# OnCo record smad3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/smad3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "smad3" ;
  schema:name "SMAD3"@en ;
  schema:alternateName "SMAD family member 3"@en, "JV15-2"@en, "HsT17436"@en, "MADH3"@en, "SMAD3" ;
  schema:description "SMAD3 (SMAD family member 3) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer, Pancreatic ductal adenocarcinoma, Skin cancer and 4 more."@en ;
  schema:url <https://onco.cc/targets/smad3/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6769>, <https://www.uniprot.org/uniprotkb/P84022/entry>, <https://www.ncbi.nlm.nih.gov/gene/4088>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166949> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6769>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166949>, <https://www.uniprot.org/uniprotkb/P84022/entry>, <https://www.ncbi.nlm.nih.gov/gene/4088> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/melanoma/> .