# OnCo record smarca4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/smarca4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "smarca4" ;
  schema:name "SMARCA4"@en ;
  schema:alternateName "SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4"@en, "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4"@en, "hSNF2b"@en, "BRG1"@en, "BAF190"@en, "SNF2"@en, "SWI2"@en, "SNF2-BETA"@en, "SNF2LB"@en, "FLJ39786"@en, "SNF2L4"@en, "SMARCA4" ;
  schema:description "SMARCA4 is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response."@en ;
  schema:url <https://onco.cc/targets/smarca4/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11100>, <https://www.uniprot.org/uniprotkb/P51532/entry>, <https://www.ncbi.nlm.nih.gov/gene/6597>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000127616> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11100>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000127616>, <https://www.uniprot.org/uniprotkb/P51532/entry>, <https://www.ncbi.nlm.nih.gov/gene/6597> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/neuroendocrine/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/urothelial/> ;
  onco:pathways <https://onco.cc/pathways/swi-snf-chromatin/> ;
  onco:trials <https://onco.cc/trials/nct03213665/> .