# OnCo record smcc (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/smcc/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "smcc" ;
  schema:name "SMCC (thioether, non-cleavable)"@en ;
  schema:alternateName "thioether linker"@en, "MCC"@en ;
  schema:description "SMCC is the non-cleavable thioether linker in Kadcyla: the payload is freed only when the whole antibody is digested, so nothing leaks to neighbours."@en ;
  schema:url <https://onco.cc/terms/smcc/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Succinimidyl_4-(N-maleimidomethyl)cyclohexane-1-carboxylate> ;
  schema:citation <https://en.wikipedia.org/wiki/Succinimidyl_4-(N-maleimidomethyl)cyclohexane-1-carboxylate> ;
  onco:related <https://onco.cc/terms/dm1/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:drugs <https://onco.cc/drugs/trastuzumab-emtansine/> ;
  onco:terms <https://onco.cc/terms/linker/> .