# OnCo record sorafenib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/sorafenib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "sorafenib" ;
  schema:name "Sorafenib"@en ;
  schema:description "The first drug ever to extend life in advanced liver cancer (2007), now mostly a comparator arm that newer combinations are measured against."@en ;
  schema:url <https://onco.cc/drugs/sorafenib/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Sorafenib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q421136> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Sorafenib> ;
  onco:status "approved" ;
  onco:modality "Small-molecule multi-kinase inhibitor (VEGFR, PDGFR, RAF)" ;
  schema:alternateName "Nexavar" ;
  onco:approval "US 2005: Advanced RCC", "US 2007: Unresectable HCC", "US 2013: Radioiodine-refractory differentiated thyroid cancer" ;
  onco:cancers <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/hcc-advanced/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/papillary-thyroid-cancer/>, <https://onco.cc/cancers/follicular-thyroid-cancer/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/>, <https://onco.cc/technologies/antiangiogenic/> ;
  onco:targets <https://onco.cc/targets/vegf/>, <https://onco.cc/targets/braf/> ;
  onco:companies <https://onco.cc/companies/bayer/>, <https://onco.cc/companies/natco/> ;
  onco:trials <https://onco.cc/trials/sharp/>, <https://onco.cc/trials/nct03755791/>, <https://onco.cc/trials/nct05822752/> .