# OnCo record spry4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/spry4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "spry4" ;
  schema:name "SPRY4"@en ;
  schema:alternateName "sprouty RTK signaling antagonist 4"@en, "SPRY4" ;
  schema:description "SPRY4 is a feedback brake on growth-factor signalling that the MAPK pathway switches on, so its expression is a read-out of how active that pathway is."@en ;
  schema:url <https://onco.cc/targets/spry4/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:15533>, <https://www.uniprot.org/uniprotkb/Q9C004/entry> ;
  onco:tag "cansim-terms" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:15533>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000187678>, <https://www.uniprot.org/uniprotkb/Q9C004/entry>, <https://www.ncbi.nlm.nih.gov/gene/81848> ;
  onco:related <https://onco.cc/targets/spry2/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/> ;
  onco:terms <https://onco.cc/terms/co-amplification/>, <https://onco.cc/terms/cancer-ai-vocabulary/>, <https://onco.cc/terms/pathway-activation-state/> .