# OnCo record src (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/src/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "src" ;
  schema:name "SRC family kinases"@en ;
  schema:description "The first cancer gene ever identified, a kinase that relays growth, adhesion and movement signals. Dasatinib and bosutinib were designed as BCR::ABL1 drugs but also hit SRC-family kinases, part of the reason they work when imatinib has failed."@en ;
  schema:url <https://onco.cc/targets/src/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Proto-oncogene_tyrosine-protein_kinase_Src>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11283>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000197122>, <https://www.uniprot.org/uniprotkb/P12931/entry>, <https://www.ncbi.nlm.nih.gov/gene/6714> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P12931/entry> ;
  schema:alternateName "SRC" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1985"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/cml/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:drugs <https://onco.cc/drugs/dasatinib/>, <https://onco.cc/drugs/bosutinib/> .