# OnCo record ss18-ssx-fusion (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/ss18-ssx-fusion/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "ss18-ssx-fusion" ;
  schema:name "SS18::SSX fusion (synovial sarcoma)"@en ;
  schema:alternateName "SS18-SSX"@en, "SS18::SSX1"@en, "SS18::SSX2"@en, "SS18::SSX4"@en, "SYT-SSX"@en, "SYT::SSX"@en, "t(X;18)"@en, "t(X;18)(p11;q11)"@en, "SS18-SSX antibody"@en, "SS18-SSX immunohistochemistry"@en, "synovial sarcoma fusion"@en, "TLE1"@en ;
  schema:description "Every true synovial sarcoma carries a fusion between the SS18 gene on chromosome 18 and an SSX gene on the X chromosome; finding it by FISH, RNA sequencing or a newer antibody stain confirms a diagnosis that pathologists otherwise struggle with, and it also flags the tumour for the MAGE-A4 and NY-ESO-1 cell therapies that work almost only in this disease."@en ;
  schema:url <https://onco.cc/terms/ss18-ssx-fusion/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  onco:related <https://onco.cc/terms/gene-fusion/>, <https://onco.cc/terms/fish/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/terms/ihc/>, <https://onco.cc/targets/mage-a4/>, <https://onco.cc/terms/hla-a02-restriction/>, <https://onco.cc/drugs/afamitresgene-autoleucel/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/doxorubicin/> ;
  onco:cancers <https://onco.cc/cancers/synovial-sarcoma/> .
