# OnCo record sterile-injectable-generics-manufacturing (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/sterile-injectable-generics-manufacturing/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "sterile-injectable-generics-manufacturing" ;
  schema:name "Generic sterile injectables (the 2023 platinum shortage)"@en ;
  schema:description "Cisplatin, carboplatin, methotrexate and most old chemotherapy drugs are cheap vials made by very few factories under sterile conditions. In 2023 one Indian plant stopped and American cancer centres ran short of both platinum drugs for months."@en ;
  schema:url <https://onco.cc/technologies/sterile-injectable-generics-manufacturing/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Cisplatin%20Injection&st=c>, <https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Carboplatin%20Injection&st=c>, <https://www.ashp.org/drug-shortages/current-shortages>, <https://www.fda.gov/drugs/drug-shortages/report-drug-shortages-root-causes-and-potential-solutions> ;
  onco:status "standard-of-care" ;
  onco:tag "manufacturing-wave" ;
  onco:cancers <https://onco.cc/cancers/testicular/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/head-and-neck/> ;
  onco:sections <https://onco.cc/fronts/chemotherapy/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/sterile-fill-finish/>, <https://onco.cc/technologies/generic-drug-shortage-response/>, <https://onco.cc/technologies/small-molecule-api-synthesis/>, <https://onco.cc/technologies/pharmaceutical-gmp-inspections/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/platinum/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/oxaliplatin/>, <https://onco.cc/drugs/methotrexate/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/cytarabine/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/etoposide/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/leucovorin/> ;
  onco:companies <https://onco.cc/companies/intas/>, <https://onco.cc/companies/fresenius-kabi/>, <https://onco.cc/companies/pfizer/>, <https://onco.cc/companies/teva/>, <https://onco.cc/companies/hikma/>, <https://onco.cc/companies/amneal/>, <https://onco.cc/companies/sandoz/>, <https://onco.cc/companies/viatris/>, <https://onco.cc/companies/dr-reddys/>, <https://onco.cc/companies/civica-rx/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-drug-pricing/>, <https://onco.cc/bottlenecks/b-global-access/> .