# OnCo record stk11-keap1 (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/stk11-keap1/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "stk11-keap1" ;
  schema:name "STK11 / KEAP1 co-mutations"@en ;
  schema:alternateName "STK11"@en, "KEAP1"@en, "co-mutation"@en, "co-mutations"@en, "co-mutated"@en, "STK11/KEAP1"@en, "LKB1"@en, "SMARCA4"@en ;
  schema:description "Two genes whose loss, often alongside a KRAS mutation, makes lung cancer 'cold' to immunotherapy and shortens survival on standard treatment. They are the reason two KRAS-mutant lung cancers can behave completely differently."@en ;
  schema:url <https://onco.cc/terms/stk11-keap1/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/STK11> ;
  schema:citation <https://en.wikipedia.org/wiki/STK11> ;
  onco:related <https://onco.cc/terms/kras-mutation-subtypes/>, <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/pd-l1-testing/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/>, <https://onco.cc/fronts/targeted-therapy/> ;
  onco:targets <https://onco.cc/targets/kras/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-skoulidis-kras-co-mutation-subsets-cancer-discov-2015/>, <https://onco.cc/key-papers/paper-kras-nsclc-cancer-discov-2018/>, <https://onco.cc/key-papers/paper-arbour-kras-co-mutation-outcomes-ccr-2018/>, <https://onco.cc/key-papers/paper-ricciuti-stk11-keap1-kras-immunotherapy-jto-2022/>, <https://onco.cc/key-papers/paper-keynote-189-407-tmb-jtocrr-2023/> .