# OnCo record stk11 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/stk11/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "stk11" ;
  schema:name "STK11"@en ;
  schema:alternateName "serine/threonine kinase 11"@en, "Serine/threonine-protein kinase STK11"@en, "LKB1"@en, "STK11" ;
  schema:description "STK11 is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor, a biomarker and a DNA repair gene, and clinical evidence ties its variants to diagnosis, prognosis or drug response."@en ;
  schema:url <https://onco.cc/targets/stk11/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11389>, <https://www.uniprot.org/uniprotkb/Q15831/entry>, <https://www.ncbi.nlm.nih.gov/gene/6794>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000118046> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11389>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000118046>, <https://www.uniprot.org/uniprotkb/Q15831/entry>, <https://www.ncbi.nlm.nih.gov/gene/6794> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/anal/>, <https://onco.cc/cancers/thyroid/> ;
  onco:pathways <https://onco.cc/pathways/keap1-nrf2/>, <https://onco.cc/pathways/lipid-metabolism-cancer/> ;
  onco:trials <https://onco.cc/trials/nct05276726/>, <https://onco.cc/trials/nct05445843/>, <https://onco.cc/trials/nct05887492/>, <https://onco.cc/trials/nct06008093/> .