# OnCo record supremo (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/supremo/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "supremo", "ISRCTN61145589" ;
  schema:name "SUPREMO (BIG 2-04)"@en ;
  schema:alternateName "SUPREMO trial"@en, "BIG 2-04"@en, "Selective Use of Postoperative Radiotherapy aftEr MastectOmy"@en ;
  schema:description "For women with one to three involved nodes or a larger node-negative tumour, radiotherapy to the chest wall after mastectomy did not help them live longer. It roughly halved the small chance of the cancer returning on the chest wall, from one in forty to one in ninety."@en ;
  schema:url <https://onco.cc/trials/supremo/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://www.isrctn.com/ISRCTN61145589>, <https://doi.org/10.1056/NEJMoa2412225>, <https://doi.org/10.1016/j.radonc.2026.111416> ;
  onco:status "negative" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/hypofractionated-radiotherapy/> ;
  onco:companies <https://onco.cc/companies/big/> ;
  onco:terms <https://onco.cc/terms/post-mastectomy-radiotherapy/>, <https://onco.cc/terms/mastectomy/>, <https://onco.cc/terms/breast-reconstruction/> ;
  onco:trials <https://onco.cc/trials/nsabp-b51/>, <https://onco.cc/trials/ma-20/>, <https://onco.cc/trials/eortc-22922/> .