# OnCo record synergy-custirsen (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/synergy-custirsen/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "synergy-custirsen", "NCT01188187" ;
  schema:name "SYNERGY"@en ;
  schema:alternateName "SYNERGY"@en, "custirsen with first-line docetaxel"@en ;
  schema:description "Blocking the survival protein clusterin did not make chemotherapy work better for advanced prostate cancer."@en ;
  schema:url <https://onco.cc/trials/synergy-custirsen/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01188187>, <https://doi.org/10.1016/S1470-2045(17)30168-7> ;
  onco:status "negative" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:technologies <https://onco.cc/technologies/antisense-sirna/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:drugs <https://onco.cc/drugs/custirsen/>, <https://onco.cc/drugs/docetaxel/>, <https://onco.cc/drugs/prednisone/> ;
  onco:companies <https://onco.cc/companies/achieve-life-sciences/> ;
  onco:terms <https://onco.cc/terms/castration-resistance/> ;
  onco:trials <https://onco.cc/trials/affinity-custirsen/>, <https://onco.cc/trials/tax-327/> .