# OnCo record synovial-sarcoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/synovial-sarcoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "synovial-sarcoma" ;
  schema:name "Synovial sarcoma"@en ;
  schema:alternateName "SS18-SSX sarcoma"@en ;
  schema:description "Synovial sarcoma is a young person's sarcoma driven by a single fusion gene, SS18-SSX, that scrambles how genes are switched on. It is treated with surgery, radiotherapy and ifosfamide-based chemotherapy, and in 2024 it became the first solid tumour with an approved engineered T-cell receptor therapy."@en ;
  schema:url <https://onco.cc/cancers/synovial-sarcoma/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Synovial_sarcoma> ;
  schema:citation <https://en.wikipedia.org/wiki/Synovial_sarcoma> ;
  onco:tag "subtype-page" ;
  onco:related <https://onco.cc/cancers/extremity-soft-tissue-sarcoma/>, <https://onco.cc/cancers/malignant-peripheral-nerve-sheath-tumour/>, <https://onco.cc/cancers/epithelioid-sarcoma/>, <https://onco.cc/cancers/alveolar-soft-part-sarcoma/>, <https://onco.cc/cancers/leiomyosarcoma/>, <https://onco.cc/cancers/undifferentiated-pleomorphic-sarcoma/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-spearhead-1-afami-cel-sarcoma-lancet-2024/>, <https://onco.cc/key-papers/paper-eortc-62012-doxorubicin-ifosfamide-judson-lancet-oncol-2014/>, <https://onco.cc/key-papers/paper-clark-syt-ssx-synovial-sarcoma-nat-genet-1994/>, <https://onco.cc/key-papers/paper-dangelo-ny-eso-1-tcr-synovial-sarcoma-cancer-discov-2018/> ;
  onco:pipeline <https://onco.cc/drugs/letetresgene-autoleucel/> ;
  onco:standardOfCare <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/ifosfamide/>, <https://onco.cc/drugs/doxorubicin/>, <https://onco.cc/drugs/pazopanib/>, <https://onco.cc/drugs/trabectedin/>, <https://onco.cc/drugs/afamitresgene-autoleucel/> .