# OnCo record synthetic-lethality-approaches (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/synthetic-lethality-approaches/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "synthetic-lethality-approaches" ;
  schema:name "Synthetic lethality approaches"@en ;
  schema:description "Finding a second gene that a cancer needs only because its first gene is broken, then hitting the second one."@en ;
  schema:url <https://onco.cc/technologies/synthetic-lethality-approaches/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Synthetic_lethality> ;
  owl:sameAs <http://www.wikidata.org/entity/Q7662767> ;
  schema:citation <https://en.wikipedia.org/wiki/Synthetic_lethality> ;
  onco:status "approved" ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:targets <https://onco.cc/targets/parp/>, <https://onco.cc/targets/brca/>, <https://onco.cc/targets/atr/>, <https://onco.cc/targets/wee1/>, <https://onco.cc/targets/tp53/> ;
  onco:companies <https://onco.cc/companies/amphista-therapeutics/>, <https://onco.cc/companies/foghorn-therapeutics/>, <https://onco.cc/companies/ideaya-biosciences/>, <https://onco.cc/companies/nimbus-therapeutics/>, <https://onco.cc/companies/plexium/>, <https://onco.cc/companies/repare-therapeutics/>, <https://onco.cc/companies/tango-therapeutics/> ;
  onco:terms <https://onco.cc/terms/synthetic-lethality/> .