# OnCo record t-cell-prolymphocytic-leukaemia (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/t-cell-prolymphocytic-leukaemia/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "t-cell-prolymphocytic-leukaemia" ;
  schema:name "T-cell prolymphocytic leukaemia"@en ;
  schema:alternateName "T-PLL"@en, "T-cell prolymphocytic leukemia"@en, "T-prolymphocytic leukaemia"@en, "T-cell chronic lymphocytic leukaemia (retired term)"@en ;
  schema:description "T-cell prolymphocytic leukaemia is a rare, aggressive leukaemia of mature T cells in older adults, with a very high white cell count, a big spleen and liver, swollen nodes and sometimes skin changes. The antibody alemtuzumab given into a vein clears it in most people, but it returns within a year or two unless a stem cell transplant is done in remission."@en ;
  schema:url <https://onco.cc/cancers/t-cell-prolymphocytic-leukaemia/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/T-cell-prolymphocytic_leukemia> ;
  schema:citation <https://www.cancer.gov/types/leukemia/patient/cll-treatment-pdq>, <https://doi.org/10.1038/s41375-022-01620-2>, <https://doi.org/10.1182/blood.2019000402>, <https://doi.org/10.1093/annonc/mdx163>, <https://doi.org/10.1182/blood-2011-08-372854> ;
  onco:tag "subtype-page", "wave4", "haematologic", "rare" ;
  onco:related <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/cll/>, <https://onco.cc/cancers/sezary-syndrome/>, <https://onco.cc/cancers/t-large-granular-lymphocytic-leukaemia/>, <https://onco.cc/cancers/splenic-b-cell-lymphoma-leukaemia-prominent-nucleoli/> ;
  onco:drugs <https://onco.cc/drugs/alemtuzumab/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/ibrutinib/> ;
  onco:terms <https://onco.cc/terms/allogeneic-transplant/> ;
  onco:trials <https://onco.cc/trials/nct04496349/>, <https://onco.cc/trials/nct02029443/> ;
  onco:standardOfCare <https://onco.cc/drugs/alemtuzumab/>, <https://onco.cc/terms/allogeneic-transplant/>, <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/ibrutinib/>, <https://onco.cc/trials/nct04496349/> .