# OnCo record tacr1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/tacr1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "tacr1" ;
  schema:name "NK1 receptor (TACR1)"@en ;
  schema:description "The substance P receptor that drives the delayed nausea felt in the days after chemotherapy. Aprepitant and netupitant block it and are combined with a 5-HT3 blocker and dexamethasone for the most nausea-provoking regimens."@en ;
  schema:url <https://onco.cc/targets/tacr1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tachykinin_receptor_1>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11526>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115353>, <https://www.uniprot.org/uniprotkb/P25103/entry>, <https://www.ncbi.nlm.nih.gov/gene/6869> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P25103/entry> ;
  schema:alternateName "TACR1" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1991"^^xsd:gYear ;
  onco:related <https://onco.cc/targets/htr3a/> ;
  onco:drugs <https://onco.cc/drugs/aprepitant/>, <https://onco.cc/drugs/netupitant-palonosetron/>, <https://onco.cc/drugs/rolapitant/>, <https://onco.cc/drugs/dexamethasone/> .