# OnCo record talicabtagene-autoleucel (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/talicabtagene-autoleucel/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "talicabtagene-autoleucel" ;
  schema:name "Talicabtagene autoleucel"@en ;
  schema:alternateName "tali-cel"@en, "actalycabtagene autoleucel (earlier name)"@en, "HCAR19"@en, "NexCAR19" ;
  schema:description "India's first home-grown CAR-T cell therapy, approved in 2023 for relapsed leukaemia and lymphoma, made in Mumbai for roughly a tenth of what the same kind of treatment costs in the US."@en ;
  schema:url <https://onco.cc/drugs/talicabtagene-autoleucel/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://immunoact.com>, <https://doi.org/10.1016/S2352-3026(24)00377-6>, <https://doi.org/10.1016/S2352-3026(25)00040-7> ;
  onco:status "approved" ;
  onco:modality "CAR-T (CD19, humanised)" ;
  onco:approval "IN 2023: Relapsed or refractory B-cell lymphoma and B-cell acute lymphoblastic leukaemia" ;
  onco:related <https://onco.cc/drugs/tisagenlecleucel/>, <https://onco.cc/ideas/idea-reg-lmic-public-cart-manufacturing/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/car-t/>, <https://onco.cc/technologies/point-of-care-cell-manufacturing/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:companies <https://onco.cc/companies/immunoact/>, <https://onco.cc/companies/cipla/> ;
  onco:institutions <https://onco.cc/institutions/tata-memorial/>, <https://onco.cc/institutions/actrec/>, <https://onco.cc/institutions/iit-bombay/> ;
  onco:terms <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/> ;
  onco:trials <https://onco.cc/trials/talicel-phase-1-2/> ;
  onco:people <https://onco.cc/people/purwar-rahul/>, <https://onco.cc/people/jain-hasmukh/>, <https://onco.cc/people/narula-gaurav/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-manufacturing-cell-therapy/>, <https://onco.cc/bottlenecks/b-global-access/>, <https://onco.cc/bottlenecks/b-drug-pricing/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-jain-talicabtagene-lancet-haem-2025/> .