# OnCo record tamoxifen (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/tamoxifen/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "tamoxifen" ;
  schema:name "Tamoxifen"@en ;
  schema:description "The original targeted cancer drug (1977): a pill that blocks oestrogen's effect on breast cancer and halves recurrence, still essential for premenopausal women."@en ;
  schema:url <https://onco.cc/drugs/tamoxifen/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tamoxifen> ;
  owl:sameAs <http://www.wikidata.org/entity/Q412178> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Tamoxifen> ;
  onco:status "approved" ;
  onco:modality "Small-molecule SERM" ;
  schema:alternateName "Nolvadex" ;
  onco:approval "US 1977: Advanced breast cancer", "US 1998: Risk reduction in high-risk women" ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/endocrine-therapy/>, <https://onco.cc/technologies/chemoprevention/> ;
  onco:targets <https://onco.cc/targets/estrogen-receptor/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/> ;
  onco:trials <https://onco.cc/trials/soft-text/>, <https://onco.cc/trials/dbcg-82bc/>, <https://onco.cc/trials/nct05768139/>, <https://onco.cc/trials/nct06979596/>, <https://onco.cc/trials/nct05774951/>, <https://onco.cc/trials/nct04906395/>, <https://onco.cc/trials/nct07287098/>, <https://onco.cc/trials/nct06492616/>, <https://onco.cc/trials/nct02747004/>, <https://onco.cc/trials/nct05514054/> .