# OnCo record tasonermin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/tasonermin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "tasonermin" ;
  schema:name "Tasonermin"@en ;
  schema:alternateName "Recombinant TNF-alpha-1a"@en, "rTNF-alpha"@en, "Beromun" ;
  schema:description "Beromun is a recombinant form of the immune protein TNF-alpha, pumped with the chemotherapy melphalan through the isolated blood supply of an arm or leg to shrink soft-tissue sarcomas so that the limb can be saved rather than amputated."@en ;
  schema:url <https://onco.cc/drugs/tasonermin/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tasonermin> ;
  schema:citation <https://www.ema.europa.eu/en/medicines/human/EPAR/beromun> ;
  onco:status "approved" ;
  onco:tag "ema-list" ;
  onco:modality "Recombinant tumour necrosis factor alpha for isolated limb perfusion" ;
  onco:approval "EU 1999: Irresectable soft-tissue sarcoma of the limbs with melphalan via isolated limb perfusion, as an adjunct to surgery or for palliation" ;
  onco:related <https://onco.cc/drugs/melphalan/> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/isolated-limb-perfusion/>, <https://onco.cc/technologies/cytokine-therapy/> ;
  onco:companies <https://onco.cc/companies/boehringer-ingelheim/> ;
  onco:terms <https://onco.cc/terms/limb-salvage-term/> .