# OnCo record tasuku-honjo (person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/people/tasuku-honjo/>
  a schema:Person ;
  onco:kind "person" ;
  schema:identifier "tasuku-honjo" ;
  schema:name "Tasuku Honjo"@en ;
  schema:description "He discovered the PD-1 molecule on T cells in 1992 and showed it acts as a brake on immune attack. Blocking it produced nivolumab and pembrolizumab, now used across dozens of cancers; Nobel Prize 2018."@en ;
  schema:url <https://onco.cc/people/tasuku-honjo/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tasuku_Honjo> ;
  owl:sameAs <http://www.wikidata.org/entity/Q2395341> ;
  schema:citation <https://en.wikipedia.org/wiki/Tasuku_Honjo>, <https://www.nobelprize.org/prizes/medicine/2018/honjo/facts/> ;
  onco:tag "hero", "pioneer" ;
  schema:jobTitle "Immunologist who discovered PD-1 and opened the way to anti-PD-1 therapy" ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/pdl1/> ;
  onco:drugs <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:institutions <https://onco.cc/institutions/kyoto-university-hospital/> ;
  onco:people <https://onco.cc/people/james-allison/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-immunotherapy-response/> ;
  schema:affiliation <https://onco.cc/institutions/kyoto-university-hospital/> .