# OnCo record tcr-t (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/tcr-t/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "tcr-t" ;
  schema:name "TCR-T cell therapy"@en ;
  schema:description "T cells engineered with a receptor that sees fragments of proteins inside the cancer cell, reaching targets CAR-T cannot."@en ;
  schema:url <https://onco.cc/technologies/tcr-t/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03967223> ;
  onco:status "approved" ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/melanoma/> ;
  onco:sections <https://onco.cc/fronts/cell-therapy/> ;
  onco:targets <https://onco.cc/targets/mage-a4/>, <https://onco.cc/targets/gp100/>, <https://onco.cc/targets/kras/>, <https://onco.cc/targets/tp53/> ;
  onco:drugs <https://onco.cc/drugs/afamitresgene-autoleucel/> ;
  onco:companies <https://onco.cc/companies/affini-t-therapeutics/>, <https://onco.cc/companies/neogene-therapeutics/>, <https://onco.cc/companies/invocata/>, <https://onco.cc/companies/alaunos/>, <https://onco.cc/companies/medigene/>, <https://onco.cc/companies/anocca/> ;
  onco:dependsOn <https://onco.cc/technologies/apheresis-starting-material/>, <https://onco.cc/technologies/viral-vector-manufacturing/>, <https://onco.cc/technologies/cell-therapy-cold-chain/>, <https://onco.cc/technologies/cell-therapy-release-testing/> .