# OnCo record tfe3-rearranged-renal-cell-carcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/tfe3-rearranged-renal-cell-carcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "tfe3-rearranged-renal-cell-carcinoma" ;
  schema:name "TFE3-rearranged (translocation) renal cell carcinoma"@en ;
  schema:alternateName "Translocation renal cell carcinoma"@en, "Xp11 translocation renal cell carcinoma"@en, "MiT family translocation renal cell carcinoma"@en, "TFE3-translocation RCC"@en, "TFEB-altered renal cell carcinoma"@en, "Translocation (TFE3/TFEB)"@en, "Translocation Renal Cell Carcinoma"@en ;
  schema:description "Translocation renal cell carcinoma is a rare kidney cancer, more often seen in children and young adults, driven by a rearrangement of the TFE3 gene (or its relative TFEB). It can look like clear cell or papillary kidney cancer under the microscope, so it is found by testing for the gene. There is no standard treatment for advanced disease, which is treated with the usual kidney cancer drugs."@en ;
  schema:url <https://onco.cc/cancers/tfe3-rearranged-renal-cell-carcinoma/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Renal_cell_carcinoma> ;
  schema:citation <https://www.cancer.gov/types/kidney/patient/kidney-treatment-pdq>, <https://doi.org/10.1016/j.eururo.2022.06.016>, <https://doi.org/10.1038/s41467-021-25618-z>, <https://doi.org/10.1158/1541-7786.mcr-18-1235> ;
  onco:tag "subtype-page", "wave4", "kidney", "rare" ;
  onco:related <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/clear-cell-rcc/>, <https://onco.cc/cancers/papillary-rcc/>, <https://onco.cc/cancers/wilms-tumor/>, <https://onco.cc/cancers/renal-medullary-carcinoma/> ;
  onco:targets <https://onco.cc/targets/tfe3/> ;
  onco:drugs <https://onco.cc/drugs/cabozantinib/>, <https://onco.cc/drugs/sunitinib/>, <https://onco.cc/drugs/nivolumab/> ;
  onco:trials <https://onco.cc/trials/nct06638931/> ;
  onco:standardOfCare <https://onco.cc/cancers/rcc/>, <https://onco.cc/drugs/cabozantinib/>, <https://onco.cc/drugs/sunitinib/>, <https://onco.cc/drugs/nivolumab/> .