# OnCo record tfe3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/tfe3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "tfe3" ;
  schema:name "TFE3"@en ;
  schema:alternateName "transcription factor binding to IGHM enhancer 3"@en, "Transcription factor E3"@en, "bHLHe33"@en, "TFE3" ;
  schema:description "TFE3 (Transcription factor E3) is a protein that switches other genes on and off. The public catalogues list it as a drug target and a fusion partner, and the evidence so far is association rather than a proven role. Tied to Renal cell carcinoma, Sarcomas, Colorectal cancer and 1 more."@en ;
  schema:url <https://onco.cc/targets/tfe3/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11752>, <https://www.uniprot.org/uniprotkb/P19532/entry>, <https://www.ncbi.nlm.nih.gov/gene/7030>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000068323> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11752>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000068323>, <https://www.uniprot.org/uniprotkb/P19532/entry>, <https://www.ncbi.nlm.nih.gov/gene/7030> ;
  onco:related <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/cediranib/> .
