# OnCo record tgf-beta (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/tgf-beta/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "tgf-beta" ;
  schema:name "TGF-β signalling"@en ;
  schema:description "A signal that stops normal cells from dividing but, once a cancer is established, switches sides: it builds scar-like stroma, walls out immune cells, and pushes cells into a migratory state."@en ;
  schema:url <https://onco.cc/pathways/tgf-beta/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/TGF_beta_signaling_pathway> ;
  owl:sameAs <http://www.wikidata.org/entity/Q3562192> ;
  schema:citation <https://doi.org/10.1038/nature25492> ;
  onco:tag "mechanism" ;
  onco:cancers <https://onco.cc/cancers/pancreatic/> ;
  onco:targets <https://onco.cc/targets/acvr1/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/vall-dhebron/>, <https://onco.cc/institutions/cold-spring-harbor/> ;
  onco:pathways <https://onco.cc/pathways/emt/>, <https://onco.cc/pathways/tumor-microenvironment/>, <https://onco.cc/pathways/metastatic-cascade/>, <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:terms <https://onco.cc/terms/immune-exclusion/>, <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/desmoplasia/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tauriello-tgfbeta-immune-evasion-colorectal-nature-2018/> .