# OnCo record thalidomide (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/thalidomide/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "thalidomide" ;
  schema:name "Thalidomide"@en ;
  schema:description "Thalidomide is the drug behind the 1960s birth-defect tragedy, rehabilitated as the first immunomodulatory myeloma drug and the parent of lenalidomide and pomalidomide."@en ;
  schema:url <https://onco.cc/drugs/thalidomide/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Thalidomide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q203174> ;
  schema:citation <https://en.wikipedia.org/wiki/Thalidomide> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "historic" ;
  onco:modality "Oral cereblon modulator (first IMiD)" ;
  schema:alternateName "Thalomid" ;
  onco:approval "US 1998: Erythema nodosum leprosum", "US 2006: Newly diagnosed multiple myeloma with dexamethasone", "EU 2008: Untreated multiple myeloma ≥65 or transplant-ineligible, with melphalan-prednisone" ;
  onco:acceleratedApproval "US 2006-05-25: Newly diagnosed multiple myeloma" ;
  onco:acceleratedApprovalConfirmed "US 2014-06-19: Newly diagnosed multiple myeloma" ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:technologies <https://onco.cc/technologies/protac-degrader/>, <https://onco.cc/technologies/antiangiogenic/> ;
  onco:targets <https://onco.cc/targets/ikzf1/> ;
  onco:companies <https://onco.cc/companies/bms/> .