# OnCo record tki-then-adc-lung (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/tki-then-adc-lung/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "tki-then-adc-lung" ;
  schema:name "EGFR TKI → ADC on progression"@en ;
  schema:description "After the lung cancer pill stops working, an ADC that does not care which resistance mutation emerged."@en ;
  schema:url <https://onco.cc/pairings/tki-then-adc-lung/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://doi.org/10.1200/JCO.23.01476> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:drugs <https://onco.cc/drugs/osimertinib/>, <https://onco.cc/drugs/datopotamab-deruxtecan/>, <https://onco.cc/drugs/patritumab-deruxtecan/>, <https://onco.cc/drugs/izalontamab-brengitecan/>, <https://onco.cc/drugs/amivantamab/> ;
  onco:pairs <https://onco.cc/drugs/osimertinib/>, <https://onco.cc/drugs/datopotamab-deruxtecan/> .