# OnCo record tmprss2-erg-fusion (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/tmprss2-erg-fusion/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "tmprss2-erg-fusion" ;
  schema:name "TMPRSS2-ERG fusion (and the other ETS rearrangements)"@en ;
  schema:alternateName "TMPRSS2-ERG"@en, "TMPRSS2:ERG"@en, "ERG rearrangement"@en, "ETS fusion"@en, "ERG fusion"@en, "ERG positive"@en, "ETS-positive prostate cancer"@en, "TMPRSS2-ETV1"@en ;
  schema:description "The commonest genetic change in prostate cancer, present in roughly half of tumours. Nothing treats it and it does not make the cancer more dangerous; it is useful mainly for recognising that two samples came from the same tumour."@en ;
  schema:url <https://onco.cc/biomarkers/tmprss2-erg-fusion/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1126/science.1117679>, <https://doi.org/10.1158/1055-9965.EPI-12-0042>, <https://www.cbioportal.org/study/summary?id=prad_tcga_pub> ;
  onco:tag "biomarker", "prostate" ;
  onco:related <https://onco.cc/biomarkers/spop-mutation/> ;
  onco:cancers <https://onco.cc/cancers/prostate/> ;
  onco:technologies <https://onco.cc/technologies/cytogenetics-fish/>, <https://onco.cc/technologies/rna-seq/>, <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/cgp/> ;
  onco:targets <https://onco.cc/targets/erg/>, <https://onco.cc/targets/etv1/>, <https://onco.cc/targets/tmprss2/>, <https://onco.cc/targets/androgen-receptor/> ;
  onco:pathways <https://onco.cc/pathways/prostate-cancer-signalling/>, <https://onco.cc/pathways/ar-signaling/>, <https://onco.cc/pathways/transcription-addiction/> ;
  onco:terms <https://onco.cc/terms/gene-fusion/>, <https://onco.cc/terms/fish/>, <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/driver-mutation/>, <https://onco.cc/terms/biochemical-recurrence/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tomlins-tmprss2-ets-fusion-science-2005/>, <https://onco.cc/key-papers/paper-tcga-molecular-taxonomy-primary-prostate-cell-2015/>, <https://onco.cc/key-papers/paper-pettersson-tmprss2-erg-outcome-meta-analysis-cebp-2012/>, <https://onco.cc/key-papers/paper-ren-chinese-prostate-whole-genome-eur-urol-2018/> .