# OnCo record tnbc-luminal-androgen-receptor (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/tnbc-luminal-androgen-receptor/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "tnbc-luminal-androgen-receptor" ;
  schema:name "Luminal androgen receptor triple-negative breast cancer (LAR)"@en ;
  schema:alternateName "LAR subtype"@en, "Luminal androgen receptor TNBC"@en, "Molecular apocrine breast cancer (overlapping)"@en, "AR-positive triple-negative breast cancer"@en ;
  schema:description "Luminal androgen receptor cancers are triple-negative breast cancers that behave like hormone-driven tumours run by the male hormone receptor instead of oestrogen. They are less proliferative, respond less well to chemotherapy, and have shown modest benefit from prostate cancer drugs that block the androgen receptor in phase 2 trials; none is approved for breast cancer."@en ;
  schema:url <https://onco.cc/cancers/tnbc-luminal-androgen-receptor/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Androgen_receptor> ;
  schema:citation <https://doi.org/10.1172/jci45014>, <https://doi.org/10.1371/journal.pone.0157368>, <https://doi.org/10.1158/1078-0432.ccr-13-0799>, <https://doi.org/10.1158/1078-0432.ccr-14-0432>, <https://doi.org/10.1186/bcr3421>, <https://doi.org/10.1158/1078-0432.ccr-12-3327>, <https://doi.org/10.1200/jco.2016.71.3495> ;
  onco:tag "breast", "tnbc", "subtype-page" ;
  onco:related <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/apocrine-carcinoma-breast/>, <https://onco.cc/cancers/tnbc-basal-like-1/> ;
  onco:targets <https://onco.cc/targets/androgen-receptor/> ;
  onco:drugs <https://onco.cc/drugs/bicalutamide/>, <https://onco.cc/drugs/enzalutamide/> ;
  onco:pathways <https://onco.cc/pathways/pi3k-akt-mtor/> ;
  onco:terms <https://onco.cc/terms/androgen-receptor-positive-tnbc/>, <https://onco.cc/terms/pcr/> ;
  onco:standardOfCare <https://onco.cc/trials/keynote-522/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/bicalutamide/>, <https://onco.cc/drugs/enzalutamide/>, <https://onco.cc/targets/androgen-receptor/> .