# OnCo record tng456 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/tng456/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "tng456" ;
  schema:name "TNG456"@en ;
  schema:description "TNG456 is an experimental small-molecule drug from Tango Therapeutics in phase 2 trials for non-small-cell lung cancer and glioma & glioblastoma, aimed at PRMT5 (MTAP-deleted cancers)."@en ;
  schema:url <https://onco.cc/drugs/tng456/> ;
  schema:dateModified "2026-09-11"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/search?intr=TNG456>, <https://tangotx.com/pipeline/> ;
  onco:status "phase-2" ;
  onco:tag "pipeline", "ctgov-ingest" ;
  onco:modality "small molecule" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/glioblastoma/> ;
  onco:targets <https://onco.cc/targets/prmt5-mtap/> ;
  onco:companies <https://onco.cc/companies/tango-therapeutics/> ;
  onco:trials <https://onco.cc/trials/nct06810544/> .