# OnCo record tnt (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/tnt/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "tnt", "NCT00532727" ;
  schema:name "TNT (Triple Negative Trial)"@en ;
  schema:alternateName "TNT trial"@en, "NCT00532727"@en ;
  schema:description "The UK phase 3 trial that showed carboplatin is not better than docetaxel for triple-negative breast cancer as a whole, but is for the germline BRCA1/2 subgroup, and that gave the NHS its evidence for platinum in BRCA carriers."@en ;
  schema:url <https://onco.cc/trials/tnt/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/s41591-018-0009-7>, <https://bepartofresearch.nihr.ac.uk/trial-details/trial-detail?trialId=NCT00532727>, <https://doi.org/10.1038/s41591-018-0009-7> ;
  onco:status "mixed" ;
  onco:tag "uk", "breast", "platinum" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-metastatic/> ;
  onco:technologies <https://onco.cc/technologies/platinum/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/brca/> ;
  onco:drugs <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/docetaxel/> ;
  onco:institutions <https://onco.cc/institutions/icr-london/>, <https://onco.cc/institutions/royal-marsden/>, <https://onco.cc/institutions/breast-cancer-now/> ;
  onco:terms <https://onco.cc/terms/gbrca-mutation/>, <https://onco.cc/terms/hrd/> ;
  onco:trials <https://onco.cc/trials/brocade3/>, <https://onco.cc/trials/olympiad/> ;
  onco:people <https://onco.cc/people/andrew-tutt/>, <https://onco.cc/people/jean-abraham/> .