# OnCo record total-neoadjuvant-therapy (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/total-neoadjuvant-therapy/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "total-neoadjuvant-therapy" ;
  schema:name "Total neoadjuvant therapy (TNT, rectal cancer)"@en ;
  schema:alternateName "total neoadjuvant therapy"@en, "total neoadjuvant treatment"@en, "TNT approach"@en, "short-course radiotherapy then chemotherapy"@en, "consolidation chemotherapy"@en, "induction TNT"@en, "consolidation TNT"@en, "RAPIDO"@en, "PRODIGE 23"@en, "OPRA"@en ;
  schema:description "Giving all the chemotherapy and radiotherapy for rectal cancer before surgery rather than splitting it around the operation. It improves completion of chemotherapy, shrinks more tumours completely, and makes avoiding surgery possible for some patients."@en ;
  schema:url <https://onco.cc/terms/total-neoadjuvant-therapy/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Colorectal_cancer#Rectal_cancer> ;
  schema:citation <https://en.wikipedia.org/wiki/Colorectal_cancer#Rectal_cancer>, <https://www.nice.org.uk/guidance/ng151/chapter/Recommendations>, <https://www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/chemoradiation-for-rectal-cancer> ;
  onco:related <https://onco.cc/terms/organ-preservation/>, <https://onco.cc/terms/total-mesorectal-excision/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/terms/hypofractionation/>, <https://onco.cc/terms/folfox-family/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/rectal-cancer/> ;
  onco:sections <https://onco.cc/fronts/radiation/>, <https://onco.cc/fronts/chemotherapy/> .